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Description

No reverse impact of depression liability on AC levels was found

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& Upton, R

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Results H4R expression is increased in a subset of untreated patients with active UC and is found in local proximity of activated neutrophils Histamine is increased in the mucosa of patients with active IBD, but the underlying immune mechanism to drive inflammation via histamine receptors is not well defined

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(ii) cytokine storm-induced immune-metabolic reprogramming, which could elevate kynurenine:tryptophan ratio and trigger chronic depression syndrome 729

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