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From several pieces of literature, it has been observed that the delivery of neurotrophic factors to the brain holds a promising strategy for neuroprotection and neurorestoration in PD

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

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The ratio of oxidized to reduced glutathione (GSSG/GSH ratio) is regarded as an indicator for tissue redox conditions [47,53] and it is increased at 10 to 60 min in the Aldh2*2 KI homozygous mice compared with the WT mice (Fig