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Remyelination of the superior cerebellar peduncle in old mice following demyelination induced by cuprizone

Reduced L- glutathione is one of the most powerful antioxidants

Therefore a good idea rises itself that it would be much more reasonable to synthesize the peptide fragment, which was determined by sequencing as N-terminal pentadecapeptide having amino acid sequence: GEPPPGKPADDAGLV, following with pharmacological assessment and comparison of activity

The propeptides are cleaved by endopeptidases after secretion into the extracellular space (extracellular activation) or before they are incorporated into storage vesicles (intracellular activation) [21, 22]