Many pathological states, such as cancer, Parkinson's disease, and Alzheimer's disease have been shown to be related to the redox state of cells
The second component (18.7% of the variance) loaded positively on glutathione and glutamate in the ACC and the third component (18% of the variance) loaded positively on glutamine measures in all three voxels
Symptoms of low thiamine (B1) include: A pins-and-needles sensation in your toes, burning in your feet (especially at night), muscle cramps, and heart abnormalities Confusion A hard time keeping your balance Vision changes Memory loss If you're low in riboflavin (B2) you might have: Pale skin Cracks in the corner of your mouth and on the lips Sores in the mouth, on the tongue A magenta-colored tongue Patches that appear red, greasy, or scaly on your nose, above your lips, or on your ears, eyelids, and genitals Low levels of niacin (B3) can cause: A sunburn-like rash that is worse on areas of the skin exposed to the sun An inflamed tongue Burning and sores in your mouth Burning in your throat Decreased saliva Nausea Vomiting Constipation Diarrhea, possibly with blood Fatigue Insomnia Confusion Disorientation Hallucinations Memory loss Depression Mania Paranoia Pantothenic acid (B5) deficiency can cause: Numbness or burning in your hands and feet Headache Fatigue Crankiness Restlessness Insomnia Heartburn Diarrhea Nausea and vomiting Loss of appetite Low pyridoxine (B6) symptoms are: Dermatitis A red, greasy, scaly rash Numb or prickling hands and feet A sore and red tongue Cracks in the corners of your mouth Confusion Crankiness Seizures With low biotin (B7) levels, you might notice: Hair loss Dry, scaly skin Cracking in the corners of your mouth A swollen, painful tongue Dry eyes Loss of appetite Fatigue Insomnia Depression Signs of a folate ( B9) deficiency include: Fatigue Pale skin Shortness of breath Crankiness Dizziness A red, sore tongue Mouth sores Reduced sense of taste Memory loss A hard time concentrating Confusion Muscle weakness Depression Weight loss Diarrhea Cobalamin (B12) deficiency causes: Rapid breathing Headaches Stomach upset Loss of appetite Heart palpitations Vision changes Fatigue Diarrhea A sore, red tongue Mouth sores Loss of memory Confusion Numbness or a pins-and-needles feeling Muscle weakness A hard time keeping your balance Incontinence (not able to hold your pee) Vitamin B Complex Side Effects and Risks Although B complex offers many health benefits and is essential to the bodys overall function, supplementing with B vitamins does carry some risk, especially at high dosages
Curr Pharmacol Rep 4:468481 Allmang C, Wurth L, Krol A (2009) The selenium to selenoprotein pathway in eukaryotes: more molecular partners than anticipated
