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Adverse Reaction Animals with heart or kidney disease may develop hypercalcemia Contraindications Do not use in cases of hypercalcaemia

10 Recently, several clinical trials have shown the potential effects of these medications in not only in glycemic control but also in the improvement of cardiovascular outcomes, weight loss, osteoarthritis, 11 metabolic dysfunctionassociated steatohepatitis (MASH), 12 Parkinsons disease, 13 chronic kidney disease (CKD) 14 and obstructive sleep apnea

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Randalls plaque and calcium oxalate stone formation: role for immunity and inflammation