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Current PSMA-directed strategies encompass radioligand therapies (e.g., 177Lu-PSMA-617, 225Ac-PSMA-RLT), antibody-drug conjugates (MLN2704, PSMA-MMAE), cellular immunotherapies (PSMA-CAR-T, BiTEs), and experimental modalities such as photodynamic therapy and ultrasound-mediated nanobubble ablation

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