Autofluorescence of NADH is a new biomarker for sorting and characterizing cancer stem cells in human glioma
(aligned to the definition of value added data in our framework) In the third case, utilities may perform analysis of customer-specific data, and provide recommendations based on that analysis, conditioned on utilities implementing tools to allow customers to easily share their usage data with third-party vendors including firms providing data analysis (again, aligned to the definition of value added data in our framework)
The reaction mechanism for roGFP2(S 2 ) as a model non-glutathione disulfide substrate resembles the first part of the GSH-dependent reduction of the sulfenic acid of human peroxiredoxin 6 that is catalyzed by glutathione transferase P1-1 (which shares several structural features with glutaredoxins) 7,80,81,82
Therefore, enhanced glutaminolysis might eventually contribute to the initiation and progression of cancer by stimulating cell growth via the mTORC1 pathway and enhancing aerobic glycolysis while disrupting the proper elimination of misfolded proteins, damaged DNA and organelles through the inhibition of autophagy and the DNA damage response 166